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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1423515Generated: November 3, 2026

4-[2-(cyclopropylmethoxy)-5-(difluoromethyl)phenyl]-6-methyl-5H-pyrrolo[3,2-d]pyrimidine-7-carboxylic acid → HCID 86666660, compound

https://huagongshe.com/reaction/1423515

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-[2-(cyclopropylmethoxy)-5-(difluoromethyl)phenyl]-6-methyl-5H-pyrrolo[3,2-d]pyrimidine-7-carboxylic acidHCID 67956012—
ReactantHCID 86666661HCID 86666661—
ProductHCID 86666660HCID 86666660—

Reaction Steps

Starting from 4-[2-(cyclopropylmethoxy)-5-(difluoromethyl)phenyl]-6-methyl-5H-pyrrolo[3,2-d]pyrimidine-7-carboxylic acid (example D.g1) and (1S*,2S*,4R*)-4-azido-2-methylcyclopentanamine hydrochloride (example C34) the title compound is obtained as pale yellow foam.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08927557B2
Source datasetuspto-grants-2015_01
ORD IDord-65536ea456b64d74a0ffa82e97def123
Source noteuspto-grants-2015_01