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HRID1423862

反应详情

EQUATION

反应方程式

HRID 1423862 的结构方程式

REACTANTS

反应物

1
结构：Cl.NCC(=O)N1C[C@H](NC(=O)c2ccccc2)C[C@H]1C(=O)O
HCID44563896

Glycyl-(4R)-4-benzamido-L-proline--hydrogen chloride (1/1)

C14H18ClN3O4

PRODUCTS

生成物

1
结构：Cl.NCC(=O)N1C[C@H](NC(=O)c2ccccc2)C[C@H]1C(=O)O.O
HCID68515358

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CC(C)O.O
溶剂HCID21889133

Propan-2-ol--water (1/1)

C3H10O2

PROCEDURE

实验过程

32 mg of amorphous (2S,4R)-1-(2-aminoacetyl)-4-benzamidopyrrolidine-2-carboxylic acid hydrochloride was dissolved in three volumes of an isopropanol/water (19.5:0.5 ratio by volume) mixed solvent at room temperature. The container was left open, and the crystals that had formed were collected. The crystalline solid was dried at 40-50° C. under vacuum to give crystalline (2S,4R)-1-(2-aminoacetyl)-4-benzamidopyrrolidine-2-carboxylic acid hydrochloride monohydrate.

WORKUP

后处理

  1. additionmixed solvent at room temperature
  2. waitThe container was left open
  3. customthe crystals that had formed
  4. customwere collected
  5. customThe crystalline solid was dried at 40-50° C. under vacuum