(3-Methoxyphenyl)boronic acid → HCID 178498925, compound

HRID 1423915Notes

Reaction equation

HRID 1423915 reaction equation
[CH3:1][O:2][C:3]([C:5]1[C:6](=[O:17])[S:7][C:8]2[C:13]([C:14]=1[OH:15])=[CH:12][CH:11]=[C:10](Br)[CH:9]=2)=[O:4].[CH3:18][O:19][C:20]1[CH:21]=[C:22](B(O)O)[CH:23]=[CH:24][CH:25]=1>>[CH3:1][O:2][C:3]([C:5]1[C:6](=[O:17])[S:7][C:8]2[C:13]([C:14]=1[OH:15])=[CH:12][CH:11]=[C:10]([C:24]1[CH:23]=[CH:22][CH:21]=[C:20]([O:19][CH3:18])[CH:25]=1)[CH:9]=2)=[O:4]

Participants

3

Reactant 2

HCID 2734370(3-Methoxyphenyl)boronic acidHCID 178498916HCID 178498916, compound

Product 1

HCID 178498925HCID 178498925, compound

Procedure

4-Hydroxy-7-(3-methoxy-phenyl)-2-oxo-2H-thiochromene-3-carboxylic acid methyl ester was prepared from 7-bromo-4-hydroxy-2-oxo-2H-thiochromene-3-carboxylic acid methyl ester (Example 5e) and 3-methoxyphenylboronic acid under conditions analogous to Example 7(a). MS ESI(−) m/e: 341.10 (M−1).

Sources & evidence

ORD record
ord-c81d4cc7a0b34f148e96218184c9aaec
Source dataset
uspto-grants-2015_01
Patent number
US08927591B2

Reaction notes

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