(2S)-2-(((tert-butoxy)carbonyl)amino)-3-methoxypropanoic acid → HCID 178495726, compound

HRID 1424179Notes

Reaction equation

HRID 1424179 reaction equation
C([NH:8][C@H:9]([C:13](O)=O)[CH2:10][O:11][CH3:12])(OC(C)(C)C)=O.[NH2:16][C:17]1[CH:18]=[C:19]([C:24]2[CH:29]=[CH:28][C:27]([C:30]#[N:31])=[CH:26][CH:25]=2)[CH:20]=[CH:21][C:22]=1[NH2:23]>>[NH2:8][C@H:9]([C:13]1[NH:23][C:22]2[CH:21]=[CH:20][C:19]([C:24]3[CH:25]=[CH:26][C:27]([C:30]#[N:31])=[CH:28][CH:29]=3)=[CH:18][C:17]=2[N:16]=1)[CH2:10][O:11][CH3:12]

Participants

3

Reactant 2

HCID 7016354(2S)-2-(((tert-butoxy)carbonyl)amino)-3-methoxypropanoic acidHCID 86699023HCID 86699023, compound

Product 1

HCID 178495726HCID 178495726, compound

Procedure

The title compound was prepared according to Method 1 using N-Boc-O-methyl-serine and 3′,4′-diaminobiphenyl-4-carbonitrile (Preparation 82).

Sources & evidence

ORD record
ord-e6828bf20f3c4590a50f82bc5bcd0c57
Source dataset
uspto-grants-2015_01
Patent number
US08927587B2

Reaction notes

Loading…