4-Tert-butylbenzene-1,2-diamine → HCID 178440692, compound

HRID 1424183Notes

Reaction equation

HRID 1424183 reaction equation
[CH2:1]([O:8][C:9](=[O:25])[C:10]([CH3:24])([CH3:23])[C@H:11]([NH:15]C(OC(C)(C)C)=O)[C:12](O)=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:26]([C:30]1[CH:35]=[CH:34][C:33]([NH2:36])=[C:32]([NH2:37])[CH:31]=1)([CH3:29])([CH3:28])[CH3:27]>>[NH2:15][C@H:11]([C:12]1[NH:36][C:33]2[CH:34]=[CH:35][C:30]([C:26]([CH3:29])([CH3:28])[CH3:27])=[CH:31][C:32]=2[N:37]=1)[C:10]([CH3:23])([CH3:24])[C:9]([O:8][CH2:1][C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1)=[O:25]

Participants

3

Reactant 2

HCID 4327084-Tert-butylbenzene-1,2-diamineHCID 86699102HCID 86699102, compound

Product 1

HCID 178440692HCID 178440692, compound

Procedure

The title compound was prepared according to Method 1 Steps 1 and 2 using (2S)-4-(benzyloxy)-2-[(tert-butoxycarbonyl)amino]-3,3-dimethyl-4-oxobutanoic acid (Preparation 44) and 4-tert-butyl-1,2-diaminobenzene.

Sources & evidence

ORD record
ord-f5bf1b2dfd7243bba9430b9287f57301
Source dataset
uspto-grants-2015_01
Patent number
US08927587B2

Reaction notes

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