4-(1,2,3-Thiadiazol-4-yl)aniline → [7-(6-Methoxy-pyridin-3-yl)-pyrrolo[2,1-f][1,2,4]triazin-2-yl]-(4-[1,2,3]thiadiazol-4-yl-phenyl)-amine

HRID 142445Notes

Reaction equation

HRID 142445 reaction equation
[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6](-[c:9]2[cH:10][cH:11][c:12]3[cH:13][n:14][c:15]([O:18][S:19]([C:20]([F:21])([F:22])[F:23])(=[O:24])=[O:25])[n:16][n:17]23)[cH:7][n:8]1.[s:26]1[n:27][n:28][c:29](-[c:31]2[cH:32][cH:33][c:34]([NH2:37])[cH:35][cH:36]2)[cH:30]1>>[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6](-[c:9]2[cH:10][cH:11][c:12]3[cH:13][n:14][c:15]([NH:37][c:34]4[cH:33][cH:32][c:31](-[c:29]5[n:28][n:27][s:26][cH:30]5)[cH:36][cH:35]4)[n:16][n:17]23)[cH:7][n:8]1

Participants

3

Reactant 2

HCID 27391704-(1,2,3-Thiadiazol-4-yl)anilineHCID 86661684Trifluoro-methanesulfonic acid 7-(6-methoxy-pyridin-3-yl)-pyrrolo[2,1-f][1,2,4]triazin-2-yl ester

Product 1

HCID 66711571[7-(6-Methoxy-pyridin-3-yl)-pyrrolo[2,1-f][1,2,4]triazin-2-yl]-(4-[1,2,3]thiadiazol-4-yl-phenyl)-amine

Sources & evidence

ORD record
ord-23f22cc127404916bf251bfb3ee4bf01
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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