HCID 71003871, compound → HCID 70974539, compound

Participants

Reaction Steps

(S)-di-tert-butyl (6-((3,5-bis(phenylethynyl) phenyl)amino)-6-oxohexane-1,5-diyl)dicarbamate (0.35 g, 0.56 mmol) was reacted with neat TFA (10 mL) and the solution was stirred for 5 hours at room temperature. TFA was evaporated and the product (0.34 mg, 93%) was purified by recrystallization with ethanol: 1H-NMR (400 MHz, CD3OD) δ 7.80 (d, J=1.4 Hz, 2H), 7.52-7.55 (m, 4H), 7.45 (t, J=1.4 Hz, 1H), 7.38-7.41 (m, 6H), 4.06 (t, J=6.5 Hz, 1H), 2.96 (t, J=15.4 Hz, 2H), 1.96-2.06 (m, 2H), 1.70-1.78 (m, 2H), 1.50-1.60 (m, 2H).

Provenance & Evidence