1-(Azidomethyl)-3-(trifluoromethyl)benzene → HCID 66958114, compound

Participants

Reaction Steps

Synthesized from (iodoethynyl)cyclopropane and 3-trifluoromethyl-benzylazide using general procedure; 0.589 g, 1.498 mmol, 96%; mp=129-134° C. (dec.); IR (υ[cm−1]) 3087, 3011, 1453, 1325, 1165, 1122, 1074, 777, 701; 1H NMR (600 MHz, CDCl3) δ=7.57-7.56 (m, 2H), 7.45 (t, J=7.7, 1H), 7.39 (d, J=7.7, 1H), 5.57 (s, 2H), 1.78-1.72 (m, 1H), 1.06-1.01 (m, 2H), 0.99-0.93 (m, 2H); 13C NMR (151 MHz, CDCl3) δ=153.8, 135.6, 131.7 (q, J=32.6), 131.4, 129.7, 125.6 (q, J=3.7), 125.0 (q, J=3.9), 124.0 (q, J=272.3), 77.9, 53.7, 7.8, 7.5; HRMS (ESI-TOF) (m/z): [M+Na]+ calcd for C13H11F3IN3Na, 415.9847; found 415.9847.

Provenance & Evidence