1-(Azidomethyl)-3-(trifluoromethyl)benzene → HCID 86666370, compound

Participants

Reaction Steps

Synthesized from tris(3-iodoprop-2-ynyl)amine and 3-trifluoromethyl-benzylazide using general procedure, sample triturated with MeCN; 0.391 g, 0.352 mmol, 81%; mp=171-173° C. (dec.); IR (υ[cm−1]) 3072, 1445, 1328, 1162, 1123, 1095, 756; 1H NMR (600 MHz, CDCl3) δ=7.62 (s, 3H), 7.59 (d, J=7.7, 3H), 7.51 (d, J=7.6, 3H), 7.44 (t, J=7.7, 3H), 5.48 (s, 6H), 3.64 (s, 6H); 13C NMR (151 MHz, CDCl3) δ=149.4, 135.4, 132.3, 131.6 (q, J=32.7), 129.8, 125.9 (q, J=3.6), 125.8 (q, J=3.5), 123.8 (q, J=272.5), 81.2, 53.6, 48.2; HRMS (ESI-TOF) (m/z): [M+H]+ calcd for C33H25F9I3N10, 1112.9249; found 1112.9249.

Provenance & Evidence