Methanol → 1-[4-(2-Amino-phenyl)-piperazin-1-yl]-2-(3,5-dimethyl-pyrazol-1-yl)-ethanone

HRID 142470Notes

Reaction equation

HRID 142470 reaction equation
[BH4-:26].[CH3:1][c:2]1[n:3][n:4]([CH2:8][C:9](=[O:10])[N:11]2[CH2:12][CH2:13][N:14]([c:17]3[c:18]([N+:23]([O-:24])=[O:25])[cH:19][cH:20][cH:21][cH:22]3)[CH2:15][CH2:16]2)[c:5]([CH3:7])[cH:6]1.[CH3:28][OH:29].[Na+:27]>>[CH3:1][c:2]1[n:3][n:4]([CH2:8][C:9](=[O:10])[N:11]2[CH2:12][CH2:13][N:14]([c:17]3[c:18]([NH2:23])[cH:19][cH:20][cH:21][cH:22]3)[CH2:15][CH2:16]2)[c:5]([CH3:7])[cH:6]1

Participants

5

Reactant 4

HCID 887MethanolHCID 923Sodium ionHCID 28123BorohydrideHCID 270079912-(3,5-Dimethyl-pyrazol-1-yl)-1-[4-(2-nitro-phenyl)-piperazin-1-yl]-ethanone

Product 1

HCID 595487551-[4-(2-Amino-phenyl)-piperazin-1-yl]-2-(3,5-dimethyl-pyrazol-1-yl)-ethanone

Sources & evidence

ORD record
ord-a3aadfe815ed4ec5aef2c3fd67a11d9b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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