Diethyl Ether → HCID 23439185, compound

Participants

Reaction Steps

60 ml of dry diethyl ether and 14.0 gram (0.063 mole) of chlorocyclohexyldiethoxysilane (d) were charged in a 250 ml flask equipped with a reflux condenser and a stirring apparatus in an atmosphere of nitrogen and the above prepared solution of cyclopentyl magnesium chloride (2nd Grignard reagent) was slowly added while keeping the internal temperature below 10° C. After completion of addition stirring was carried out at room temperature for 6 hours and at reflux temperature for 5 hours. To the resulting reaction mass 10-20 ml of saturated aqueous ammonium chloride solution was added drop wise to dissolve magnesium salt. The organic layer was separated from the aqueous phase, dried and evaporated to give crude cyclopentylisobutyldiethoxysilane. This crude was purified by fractional distillation under reduced pressure, yielding 12 gram (75%) of pure cyclopentylisobutyldiethoxysilane.

Provenance & Evidence