HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Bromo-4-nitrobenzene → 4-Nitrophenol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Bromo-4-nitrobenzene | HCID 11466 | — |
| Reactant | 1-Iodo-4-nitrobenzene | HCID 12495 | — |
| Reactant | Cesium hydroxide | HCID 62750 | — |
| Product | 4-Nitrophenol | HCID 980 | — |
Reaction Steps
Following general operating mode A, 1-iodo-4-nitrobenzene or 1-bromo-4-nitrobenzene (249 mg or 202 mg, 1.0 mmol) were reacted at 110° C. with cesium hydroxide to obtain the expected product in the form of a yellow solid with respective yields of 90% and 82% (ethyl acetate/heptane 20:80).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08927779B2 |
| Source dataset | uspto-grants-2015_01 |
| ORD ID | ord-ba47fa25501645e28cc4bd05524c9803 |
| Source note | uspto-grants-2015_01 |