HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Bromo-3-methylbutan-2-one → 2-(3-Methyl-2-oxobutyl)-1h-isoindole-1,3(2h)-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Bromo-3-methylbutan-2-one | HCID 10899037 | — |
| Reactant | Phthalimide potassium salt | HCID 24194345 | — |
| Product | 2-(3-Methyl-2-oxobutyl)-1h-isoindole-1,3(2h)-dione | HCID 277811 | 74.1% |
Reaction Steps
The same operation as in Example (15b) was performed using 1-bromo-3-methylbutan-2-one obtained in Example (35a) (3.94 g, 23.9 mmol) and potassium phthalimide (4.4 g, 23.8 mmol), to obtain 4.08 g of the title compound as a white solid (74%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08927588B2 |
| Source dataset | uspto-grants-2015_01 |
| ORD ID | ord-6a293d2b6a3c49d798a810cf1f8b1e2c |
| Source note | uspto-grants-2015_01 |