HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfuric Acid → 5-Methyl-4-(trifluoromethyl)-1H-imidazole-2-carbaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | 2-(dimethoxymethyl)-5-methyl-4-(trifluoromethyl)-1H-imidazole | HCID 67549218 | — |
| Product | 5-Methyl-4-(trifluoromethyl)-1H-imidazole-2-carbaldehyde | HCID 86648481 | 7.9% |
Reaction Steps
The same operation as in Example (33b) was performed using 2-(dimethoxymethyl)-5-methyl-4-(trifluoromethyl)-1H-imidazole obtained in Example (36b) (about 2.17 mmol) and 2 N sulfuric acid (15 mL), to obtain 30.5 mg of the title compound as a white solid (7.9%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08927588B2 |
| Source dataset | uspto-grants-2015_01 |
| ORD ID | ord-c55dfe9fca174aa999afdb02641b211a |
| Source note | uspto-grants-2015_01 |