HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methyl-2-butene → 4,5-diethyl-1H-imidazole-2-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methyl-2-butene | HCID 10553 | — |
| Reactant | Sodium Chlorite | HCID 23668197 | — |
| Reactant | Monosodium phosphate | HCID 23672064 | — |
| Reactant | 4,5-Diethyl-1H-imidazole-2-carbaldehyde | HCID 86648501 | — |
| Product | 4,5-diethyl-1H-imidazole-2-carboxylic acid | HCID 68406225 | 9.4% |
Reaction Steps
The same operation as in Example (33c) was performed using 4,5-diethyl-1H-imidazole-2-carbaldehyde obtained in Example (43b) (352 mg, 2.31 mmol), sodium chlorite (420 mg, 4.64 mmol), sodium dihydrogenphosphate (725 mg, 4.64 mmol) and 2-methyl-2-butene (1 mL, 9.45 mmol), to obtain 36.7 mg of the title compound as a white solid (9.4%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08927588B2 |
| Source dataset | uspto-grants-2015_01 |
| ORD ID | ord-8d1d5da597274745b27ebc526f41ccbf |
| Source note | uspto-grants-2015_01 |