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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1425008Generated: November 1, 2026

Sodium Carbonate → HCID 86648548, compound

https://huagongshe.com/reaction/1425008

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium CarbonateHCID 10340—
ReactantEthyl 2-bromobenzo[d]thiazole-7-carboxylateHCID 67073467—
ReactantHCID 86648549HCID 86648549—
ProductHCID 86648548HCID 8664854865%

Reaction Steps

The same operation as in Example (1h) was performed using tert-butyl cis(±)-3-(butylamino)-4-{[(4-chloro-5-ethyl-1H-imidazol-2-yl)carbonyl]amino}piperidine-1-carboxylate obtained by the method described in Example (77d) (12.3 mg, 0.029 mmol), sodium carbonate (45 mg, 0.42 mmol) and ethyl 2-bromo-1,3-benzothiazole-7-carboxylate obtained in Example (1f) (10.4 mg, 0.036 mmol), to obtain 10.0 mg of the title compound (65%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08927588B2
Source datasetuspto-grants-2015_01
ORD IDord-1610571c0e6b4857adf99297ecb7a58b
Source noteuspto-grants-2015_01