Ethyl cis(+/-)-5-(4-{[(benzyloxy)carbonyl]amino}-3-methoxypiperidin-1-yl)pyridine-3-carboxylate → Ethyl cis(+/-)-5-(4-amino-3-methoxypiperidin-1-yl)pyridine-3-carboxylate

Participants

Reaction Steps

The same operation as in Example (160c) was performed using methyl cis(±)-4-(4-{[benzyloxy)carbonyl]amino}-3-methoxypiperidin-1-yl)pyridine-2-carboxylate obtained in Example (162a) (436 mg) and a 10% palladium-carbon catalyst (500 mg), to obtain 137.5 mg of the title compound as a colorless oily substance. The resulting compound was used for the next reaction without purification.

Provenance & Evidence