Toluene → Methyl 6-(4-biphenylylmethoxy)nicotinate

HRID 142535Notes

Reaction equation

HRID 142535 reaction equation
[Ag+2:30].[C:26](=[O:27])([O-:28])[O-:29].[CH3:31][c:32]1[cH:33][cH:34][cH:35][cH:36][cH:37]1.[OH:1][c:2]1[n:3][cH:4][c:5]([C:6](=[O:7])[O:8][CH3:9])[cH:10][cH:11]1.[c:12]1(-[c:20]2[cH:21][cH:22][cH:23][cH:24][cH:25]2)[cH:13][cH:14][c:15]([CH2:18][Br:19])[cH:16][cH:17]1>>[O:1]([c:2]1[n:3][cH:4][c:5]([C:6](=[O:7])[O:8][CH3:9])[cH:10][cH:11]1)[CH2:18][c:15]1[cH:14][cH:13][c:12](-[c:20]2[cH:21][cH:22][cH:23][cH:24][cH:25]2)[cH:17][cH:16]1

Participants

6

Reactant 5

HCID 1140TolueneHCID 19660Carbonate IonHCID 2577161,1'-Biphenyl, 4-(bromomethyl)-HCID 178419107HCID 178419107, compoundHCID 178498304HCID 178498304, compound

Product 1

HCID 18508353Methyl 6-(4-biphenylylmethoxy)nicotinate

Sources & evidence

ORD record
ord-e98c2806acbe4837a84e67a1d9cd11e7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

Loading…