HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisopropylethylamine → HCID 67549359, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | Ethyl 2-bromo-4-methyl-1,3-thiazole-5-carboxylate | HCID 2824057 | — |
| Reactant | tert-Butyl azetidin-3-yl(methyl)carbamate | HCID 23033645 | — |
| Product | HCID 67549359 | HCID 67549359 | 70.9% |
Reaction Steps
The same operation as in Example (217a) was performed using 3-[(tert-butoxycarbonyl)(methyl)amino]azetidine (1.31 g, 7.03 mmol), ethyl 2-bromo-4-methylthiazole-5-carboxylate (134 mg, 0.54 mmol) and diisopropylethylamine (0.19 mL, 1.07 mmol), to obtain 136 mg of the title compound as a colorless oily substance (72%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08927588B2 |
| Source dataset | uspto-grants-2015_01 |
| ORD ID | ord-2df59894f1764d2f80493d027755b66a |
| Source note | uspto-grants-2015_01 |