HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → cis(+/-)-1-(Diphenylmethyl)-2-ethylazetidin-3-yl methanesulfonate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Methanesulfonyl chloride | HCID 31297 | — |
| Reactant | cis(+/-)-1-(Diphenylmethyl)-2-ethylazetidin-3-ol | HCID 10038631 | — |
| Product | cis(+/-)-1-(Diphenylmethyl)-2-ethylazetidin-3-yl methanesulfonate | HCID 10337634 | 32.3% |
Reaction Steps
The same operation as in Example (234c) was performed using cis(±)-1-(diphenylmethyl)-2-ethylazetidin-3-ol obtained in Example (235b) (769 mg, 2.88 mmol), triethylamine (0.60 mL, 4.32 mmol) and methanesulfonyl chloride (0.29 mL, 3.74 mmol), to obtain 321 mg of the title compound as a pale yellow oily substance (32%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08927588B2 |
| Source dataset | uspto-grants-2015_01 |
| ORD ID | ord-26a83158816a4dbf9b396f5587cfe02e |
| Source note | uspto-grants-2015_01 |