HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1425463Generated: November 1, 2026
Propane sultone → 3-(5-Chloro-2,3,3-trimethyl-3H-pyrrolo[2,3-b]pyridin-7-ium-7-yl)propane-1-sulfonate
https://huagongshe.com/reaction/1425463
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Propane sultone | HCID 14264 | — |
| Reactant | 5-Chloro-2,3,3-trimethyl-3H-pyrrolo[2,3-b]pyridine | HCID 68082304 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 3-(5-Chloro-2,3,3-trimethyl-3H-pyrrolo[2,3-b]pyridin-7-ium-7-yl)propane-1-sulfonate | HCID 86699466 | 153.6% |
Reaction Steps
A mixture of 1 g of 5-chloro-2,3,3-trimethyl-3H-pyrrolo[2,3-b]pyridine and 1.60 g of 1,3-propanesultone was heated at 65° C. for 2 h. Ethyl acetate (ca. 100 mL) was added and the resulting mixture was stirred at room temperature overnight to yield 2.50 g of the product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08927719B2 |
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| Source dataset | uspto-grants-2015_01 |
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| ORD ID | ord-9404ce232cfe4acc9595803d06b484da |
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| Source note | uspto-grants-2015_01 |
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