4-(2-Carboxyethyl)benzeneboronic acid → Sodium (E)-2-((2Z,4E)-3-(4-(2-Carboxyethyl)phenyl)-5-(5-chloro-3,3-dimethyl-7-(3-sulfonatopropyl)-3H-pyrrolo[2,3-b]pyridin-7-ium-2-yl)penta-2,4-dienylidene)-3,3-dimethyl-1-(3-sulfonatopropyl)indoline-5-sulfonate
Reaction equation
C(CCC1C=C(/[C:12](/[CH:37]=[CH:38]/[C:39]2[C:40]([CH3:57])([CH3:56])[C:41]3[C:42]([N:55]=2)=[N+:43]([CH2:48][CH2:49][CH2:50][S:51]([O-:54])(=[O:53])=[O:52])[CH:44]=[C:45]([Cl:47])[CH:46]=3)=[CH:13]\[CH:14]=[C:15]2\[N:16]([CH2:30][CH2:31][CH2:32][S:33]([O-:36])(=[O:35])=[O:34])[C:17]3[C:22]([C:23]\2([CH3:25])[CH3:24])=[CH:21][C:20]([S:26]([O-:29])(=[O:28])=[O:27])=[CH:19][CH:18]=3)C=CC=1)(O)=O.[Na+:58].[Na+].[C:60]([CH2:63][CH2:64][C:65]1[CH:70]=[CH:69][C:68](B(O)O)=[CH:67][CH:66]=1)([OH:62])=[O:61]>>[C:60]([CH2:63][CH2:64][C:65]1[CH:70]=[CH:69][C:68](/[C:12](/[CH:37]=[CH:38]/[C:39]2[C:40]([CH3:57])([CH3:56])[C:41]3[C:42]([N:55]=2)=[N+:43]([CH2:48][CH2:49][CH2:50][S:51]([O-:54])(=[O:53])=[O:52])[CH:44]=[C:45]([Cl:47])[CH:46]=3)=[CH:13]\[CH:14]=[C:15]2\[N:16]([CH2:30][CH2:31][CH2:32][S:33]([O-:36])(=[O:35])=[O:34])[C:17]3[C:22]([C:23]\2([CH3:25])[CH3:24])=[CH:21][C:20]([S:26]([O-:29])(=[O:27])=[O:28])=[CH:19][CH:18]=3)=[CH:67][CH:66]=1)([OH:62])=[O:61].[Na+:58].[Na+:58]Participants
3
Reactant 2
Product 1
Procedure
Compound 12 is prepared analogously to compound 10 (Example 10), except that 4-(2-carboxyethyl)phenylboronic acid is used as a starting material.
Sources & evidence
- ORD record
- ord-d21ea99d884349aea85d7aaaad70c7e1
- Source dataset
- uspto-grants-2015_01
- Patent number
- US08927719B2
Reaction notes
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