3-(2-Carboxyethyl)phenylboronic acid → HCID 178422048, compound

HRID 1425475Notes

Reaction equation

HRID 1425475 reaction equation
C(CCCCC1C=C(/[C:14](=[CH:48]\[CH:49]=[C:50]2/[C:51]([CH3:69])([CH3:68])[C:52]3[C:53](=[N:67]/2)[N:54]([CH2:59][CH2:60][CH2:61][CH2:62][S:63]([O-:66])(=[O:65])=[O:64])[CH:55]=[C:56]([Cl:58])[CH:57]=3)/[CH:15]=[CH:16]/[C:17]2[C:25]([CH3:27])([CH3:26])[C:24]3[C:23]4[CH:28]=[C:29]([S:36]([O-:39])(=[O:38])=[O:37])[CH:30]=[C:31]([S:32]([O-:35])(=[O:34])=[O:33])[C:22]=4[CH:21]=[CH:20][C:19]=3[N+:18]=2[CH2:40][CH2:41][CH2:42][CH2:43][S:44]([O-:47])(=[O:46])=[O:45])C=CC=1)(O)=O.[Na+:70].[Na+].[Na+].B([C:76]1[CH:77]=[C:78]([CH2:82][CH2:83][C:84]([OH:86])=[O:85])[CH:79]=[CH:80][CH:81]=1)(O)O>>[C:84]([CH2:83][CH2:82][C:78]1[CH:77]=[C:76](/[C:14](=[CH:48]\[CH:49]=[C:50]2/[C:51]([CH3:69])([CH3:68])[C:52]3[C:53](=[N:67]/2)[N:54]([CH2:59][CH2:60][CH2:61][CH2:62][S:63]([O-:66])(=[O:64])=[O:65])[CH:55]=[C:56]([Cl:58])[CH:57]=3)/[CH:15]=[CH:16]/[C:17]2[C:25]([CH3:27])([CH3:26])[C:24]3[C:23]4[CH:28]=[C:29]([S:36]([O-:39])(=[O:37])=[O:38])[CH:30]=[C:31]([S:32]([O-:35])(=[O:33])=[O:34])[C:22]=4[CH:21]=[CH:20][C:19]=3[N+:18]=2[CH2:40][CH2:41][CH2:42][CH2:43][S:44]([O-:47])(=[O:45])=[O:46])[CH:81]=[CH:80][CH:79]=1)([OH:86])=[O:85].[Na+:70].[Na+:70].[Na+:70]

Participants

3

Reactant 2

HCID 38561183-(2-Carboxyethyl)phenylboronic acidHCID 178422046HCID 178422046, compound

Product 1

HCID 178422048HCID 178422048, compound

Procedure

Compound 30 is prepared analogously to compound 28 (Example 37), except that 3-(3-boronophenyl)propionic acid is used as a starting material.

Sources & evidence

ORD record
ord-aa3c6fa3bf324cfc9ff569597152376d
Source dataset
uspto-grants-2015_01
Patent number
US08927719B2

Reaction notes

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