4-(3-fluoroazetidine-1-carbonyl)-1-methyl-1H-pyrazole-5-carboxylic acid → 4-(3-Fluoro-azetidine-1-carbonyl)-2-methyl-2H-pyrazole-3-carboxylic acid [2-(3-methoxy-phenyl)-imidazo[1,2-a]pyrimidin-7-yl]-amide

HRID 142550Notes

Reaction equation

HRID 142550 reaction equation
[CH3:17][O:18][c:19]1[cH:20][c:21](-[c:25]2[n:26][c:27]3[n:28]([cH:29][cH:30][c:31]([NH2:33])[n:32]3)[cH:34]2)[cH:22][cH:23][cH:24]1.[F:1][CH:2]1[CH2:3][N:4]([C:6](=[O:7])[c:8]2[cH:9][n:10][n:11]([CH3:16])[c:12]2[C:13](=[O:14])[OH:15])[CH2:5]1>>[F:1][CH:2]1[CH2:3][N:4]([C:6](=[O:7])[c:8]2[cH:9][n:10][n:11]([CH3:16])[c:12]2[C:13](=[O:15])[NH:33][c:31]2[cH:30][cH:29][n:28]3[c:27]([n:26][c:25](-[c:21]4[cH:20][c:19]([O:18][CH3:17])[cH:24][cH:23][cH:22]4)[cH:34]3)[n:32]2)[CH2:5]1

Participants

3

Reactant 2

HCID 584467964-(3-fluoroazetidine-1-carbonyl)-1-methyl-1H-pyrazole-5-carboxylic acidHCID 673876022-(3-Methoxyphenyl)imidazo[1,2-A]pyrimidin-7-amine

Product 1

HCID 673840614-(3-Fluoro-azetidine-1-carbonyl)-2-methyl-2H-pyrazole-3-carboxylic acid [2-(3-methoxy-phenyl)-imidazo[1,2-a]pyrimidin-7-yl]-amide

Sources & evidence

ORD record
ord-5315e145d7924d0fba2da3dada196918
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

Loading…