反应详情

To N-(7-(benzyloxy)-9H-carbazol-2-yl)-N-methylformamide (110 mg, 0.33 mmol) in 50 mL MeOH was added Palladium on activated carbon (50 mg). The mixture was stirred at rt under H2 atmosphere for 15 h. Solid was filtered off and the filtrate was concentrated to afford N-(7-hydroxy-9H-carbazol-2-yl)-N-methylformamide as a brown solid (75 mg, 94%). This material was used directly for the next reaction without purification. MS (ESI) m/z 241 (M+H+).

1. filtrationSolid was filtered off
2. concentrationthe filtrate was concentrated