反应详情

To tert-butyl 2-(benzyloxy)-7-(N-methylformamido)-9H-carbazole-9-carboxylate (120 mg, 0.28 mmol) in 50 mL MeOH was added Palladium on activated carbon (50 mg). The mixture was stirred at rt under H2 atmosphere for 3 h. Solid was filtered off and the filtrate was concentrated to afford tert-butyl 2-hydroxy-7-(N-methylformamido)-9H-carbazole-9-carboxylate as a brown solid (95 mg, 100%). This material was used directly for the next reaction without purification. MS (ESI) m/z 341 (M+H+).

1. filtrationSolid was filtered off
2. concentrationthe filtrate was concentrated