反应详情

Triethyl phosphite (3 ml, 17.15 mmol) and 5-(benzyloxy)-2-(2-nitrophenyl)pyridine (0.3 g, 0.979 mmol) were heated to 125° C. for 4 hours. Let the reaction cool to room temperature. Concentrated and purified with Combiflash column using ethyl acetate followed by 15% methanol in DCM to afford 3-(benzyloxy)-5H-pyrido[3,2-b]indole (0.09 g, 0.328 mmol, 33.5% yield).

1. concentrationConcentrated
2. custompurified with Combiflash column