Thionyl Chloride → 10-Methylacridan-9-carboxylic acid chloride

HRID 1425639Notes

Reaction equation

HRID 1425639 reaction equation
[CH3:1][N:2]1[C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[CH:9]([C:16]([OH:18])=O)[C:8]2[CH:7]=[CH:6][CH:5]=[CH:4][C:3]1=2.S(Cl)([Cl:21])=O>ClCCl>[CH3:1][N:2]1[C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[CH:9]([C:16]([Cl:21])=[O:18])[C:8]2[CH:7]=[CH:6][CH:5]=[CH:4][C:3]1=2

Participants

4

Reactant 2

HCID 24386Thionyl ChlorideHCID 1039934110-Methylacridan-9-carboxylic acid

Product 1

HCID 5452072910-Methylacridan-9-carboxylic acid chloride

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

A solution of 0.35 parts of 10-methylacridan-9-carboxylic acid (77) in 20 mL dichloromethane and 1.1 parts of thionyl chloride is treated as described in Example I, to give 10-Methylacridan-9-carboxylic acid chloride.

Sources & evidence

ORD record
ord-037de5ec15f449a482da554209bd3db4
Source dataset
uspto-grants-2015_01
Patent number
US08932881B2

Reaction notes

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