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HRID 1425742作成日：2026年10月26日

4-(5-bromo-pyridin-2-ylmethoxy)-1H-pyridin-2-one → 4-(5-Bromo-pyridin-2-ylmethoxy)-1-[2-(4-hydroxymethyl-2-methyl-phenyl)-2-oxo-ethyl]-1H-pyridin-2-one

https://huagongshe.com/reaction/1425742

反応式

関与物質

役割名称HCID仕込み量
反応物4-(5-bromo-pyridin-2-ylmethoxy)-1H-pyridin-2-oneHCID 67007436—
反応物4-Benzyloxy-1-[2-(4-hydroxymethyl-2-methyl-phenyl)-2-oxo-ethyl]-1H-pyridin-2-oneHCID 86695537—
生成物4-(5-Bromo-pyridin-2-ylmethoxy)-1-[2-(4-hydroxymethyl-2-methyl-phenyl)-2-oxo-ethyl]-1H-pyridin-2-oneHCID 8669554398%

反応手順

4-(5-Bromo-pyridin-2-ylmethoxy)-1-[2-(4-hydroxymethyl-2-methyl-phenyl)-2-oxo-ethyl]-1H-pyridin-2-one is prepared following preparation 1c employing 4-(5-bromo-pyridin-2-ylmethoxy)-1H-pyridin-2-one (described in WO 09/103,478) instead of 4-benzyloxy-1H-pyridin-2-one.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US08933079B2
出典データセットuspto-grants-2015_01
ORD IDord-8a87203eab804d95936ec8482a09a814
出典メモuspto-grants-2015_01