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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1425745Generated: October 26, 2026

4-Benzyloxy-1-[2-(4-hydroxymethyl-2-methyl-phenyl)-2-oxo-ethyl]-1H-pyridin-2-one → 5-Benzyloxy-2-[2-(4-bromomethyl-2-methyl-phenyl)-2-oxo-ethyl]-2H-pyridazin-3-one

https://huagongshe.com/reaction/1425745

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Benzyloxy-1-[2-(4-hydroxymethyl-2-methyl-phenyl)-2-oxo-ethyl]-1H-pyridin-2-oneHCID 86695537—
Reactant4-Benzyloxy-1-[2-(4-bromomethyl-2-methyl-phenyl)-2-oxo-ethyl]-1H-pyridin-2-oneHCID 86695538—
Reactant5-Benzyloxy-2-[2-(4-hydroxymethyl-2-methyl-phenyl)-2-oxo-ethyl]-2H-pyridazin-3-oneHCID 86695545—
Product5-Benzyloxy-2-[2-(4-bromomethyl-2-methyl-phenyl)-2-oxo-ethyl]-2H-pyridazin-3-oneHCID 8669554693%

Reaction Steps

5-Benzyloxy-2-[2-(4-bromomethyl-2-methyl-phenyl)-2-oxo-ethyl]-2H-pyridazin-3-one is prepared following preparation 1d employing 5-benzyloxy-2-[2-(4-hydroxymethyl-2-methyl-phenyl)-2-oxo-ethyl]-2H-pyridazin-3-one (preparation 5a) instead of preparation 1c.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08933079B2
Source datasetuspto-grants-2015_01
ORD IDord-9f1c20fe3a9843cd84e027a8f9541219
Source noteuspto-grants-2015_01