HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethyl Sulfone → Pyridine, 2-bromo-6-[(methylsulfonyl)methyl]-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethyl Sulfone | HCID 6213 | — |
| Reactant | 2-Bromo-6-fluoropyridine | HCID 639438 | — |
| Product | Pyridine, 2-bromo-6-[(methylsulfonyl)methyl]- | HCID 59526086 | 70% |
Reaction Steps
The title compound was prepared from 2-bromo-6-fluoro-pyridine and dimethylsulfone following a procedure analogous to that described in Step 1 for Intermediate 14. Yield: ca. 70% of theory (crude); LC (method 3): tR=1.98 min; Mass spectrum (ESI+): m/z=250/252 (Br) [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08933072B2 |
| Source dataset | uspto-grants-2015_01 |
| ORD ID | ord-1239565467304ecc800d4057a8900213 |
| Source note | uspto-grants-2015_01 |