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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1426188Generated: October 27, 2026

1-Ethynyl-3-fluorobenzene → 6-(3-Fluoro-phenylethynyl)-2-methyl-pyrazolo[1,5-a]pyrimidine

https://huagongshe.com/reaction/1426188

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Ethynyl-3-fluorobenzeneHCID 520218—
Reactant6-Bromo-2-methylpyrazolo[1,5-a]pyrimidineHCID 15980041—
Product6-(3-Fluoro-phenylethynyl)-2-methyl-pyrazolo[1,5-a]pyrimidineHCID 53247074—

Reaction Steps

The title compound, light yellow solid, MS: m/e=252.2 (M++H+), can be prepared in accordance with the general method of example 1 from 6-bromo-2-methylpyrazolo[1,5-a]pyrimidine and 1-ethynyl-3-fluoro-benzene.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08933094B2
Source datasetuspto-grants-2015_01
ORD IDord-06bd7f55b920486da51eb7541288738e
Source noteuspto-grants-2015_01