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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1426192Generated: October 27, 2026

Benzene, 1-chloro-4-ethynyl- → 6-(4-Chloro-phenylethynyl)-2-methyl-pyrazolo[1,5-a]pyrimidine

https://huagongshe.com/reaction/1426192

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzene, 1-chloro-4-ethynyl-HCID 70118—
Reactant6-Bromo-2-methylpyrazolo[1,5-a]pyrimidineHCID 15980041—
Product6-(4-Chloro-phenylethynyl)-2-methyl-pyrazolo[1,5-a]pyrimidineHCID 53247078—

Reaction Steps

The title compound, brown solid, MS: m/e=268.1 (M+H+), can be prepared in accordance with the general method of example 1 from 6-bromo-2-methylpyrazolo[1,5-a]pyrimidine and 1-chloro-4-ethynylbenzene.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08933094B2
Source datasetuspto-grants-2015_01
ORD IDord-548a9765c2cc46e1a44c7209a2507f7a
Source noteuspto-grants-2015_01