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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1426200Generated: October 26, 2026

1-Ethynyl-4-methoxybenzene → 2-tert-Butyl-6-(4-methoxy-phenylethynyl)-pyrazolo[1,5-a]pyrimidine

https://huagongshe.com/reaction/1426200

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Ethynyl-4-methoxybenzeneHCID 251020—
Reactant6-Bromo-2-tert-butylpyrazolo[1,5-a]pyrimidineHCID 58316697—
Product2-tert-Butyl-6-(4-methoxy-phenylethynyl)-pyrazolo[1,5-a]pyrimidineHCID 53247201—

Reaction Steps

The title compound, yellow solid, MS: m/e=306.2 (M+H+), can be prepared in accordance with the general method of example 1 from 6-bromo-2-tert-butyl-pyrazolo[1,5-a]pyrimidine (example 9, step 1) and 1-ethynyl-4-methoxybenzene.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08933094B2
Source datasetuspto-grants-2015_01
ORD IDord-1fd6229a21624f098b4e8950fa7754d6
Source noteuspto-grants-2015_01