1-Ethynyl-3-methoxybenzene → HCID 53247203, compound

HRID 1426202Notes

Reaction equation

HRID 1426202 reaction equation
Br[C:2]1[CH:3]=[N:4][C:5]2[N:6]([N:8]=[C:9]([C:11]([CH3:14])([CH3:13])[CH3:12])[CH:10]=2)[CH:7]=1.[C:15]([C:17]1[CH:22]=[CH:21][CH:20]=[C:19]([O:23][CH3:24])[CH:18]=1)#[CH:16]>>[C:11]([C:9]1[CH:10]=[C:5]2[N:4]=[CH:3][C:2]([C:16]#[C:15][C:17]3[CH:22]=[CH:21][CH:20]=[C:19]([O:23][CH3:24])[CH:18]=3)=[CH:7][N:6]2[N:8]=1)([CH3:14])([CH3:13])[CH3:12]

Participants

3

Reactant 2

HCID 6407531-Ethynyl-3-methoxybenzeneHCID 583166976-Bromo-2-tert-butylpyrazolo[1,5-a]pyrimidine

Product 1

HCID 53247203HCID 53247203, compound

Procedure

The title compound, yellow solid, MS: m/e=306.2 (M+H+), can be prepared in accordance with the general method of example 1 from 6-bromo-2-tert-butyl-pyrazolo[1,5-a]pyrimidine (example 9, step 1) and 1-ethynyl-3-methoxybenzene.

Sources & evidence

ORD record
ord-f3723ee61e814759b23964c22cbed3c1
Source dataset
uspto-grants-2015_01
Patent number
US08933094B2

Reaction notes

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