2-Bromopropanedial → HCID 58316710, compound

HRID 1426214Notes

Reaction equation

HRID 1426214 reaction equation
[O:1]1[CH2:6][CH2:5][CH:4]([C:7]2[CH:8]=[C:9]([NH2:12])[NH:10][N:11]=2)[CH2:3][CH2:2]1.[Br:13][CH:14]([CH:17]=O)[CH:15]=O>>[Br:13][C:14]1[CH:15]=[N:12][C:9]2[N:10]([N:11]=[C:7]([CH:4]3[CH2:3][CH2:2][O:1][CH2:6][CH2:5]3)[CH:8]=2)[CH:17]=1

Participants

3

Reactant 2

HCID 749452-BromopropanedialHCID 178507311HCID 178507311, compound

Product 1

HCID 58316710HCID 58316710, compound

Procedure

The title compound, light brown solid, MS: m/e=284.0 (M+H+), can be prepared in accordance with the general method of example 9, step 1 from 5-(tetrahydro-pyran-4-yl)-2H-pyrazol-3-ylamine (example 26, step 1) and 2-bromomalonaldehyde.

Sources & evidence

ORD record
ord-c1c2ef49ac6147219af2046dd4fda9b9
Source dataset
uspto-grants-2015_01
Patent number
US08933094B2

Reaction notes

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