Benzenamine, 3-ethynyl- → HCID 53247453, compound

HRID 1426224Notes

Reaction equation

HRID 1426224 reaction equation
Br[C:2]1[CH:3]=[N:4][C:5]2[N:6]([N:8]=[C:9]([C:11]([CH3:14])([CH3:13])[CH3:12])[CH:10]=2)[CH:7]=1.[C:15]([C:17]1[CH:18]=[C:19]([CH:21]=[CH:22][CH:23]=1)[NH2:20])#[CH:16]>>[C:11]([C:9]1[CH:10]=[C:5]2[N:4]=[CH:3][C:2]([C:16]#[C:15][C:17]3[CH:18]=[C:19]([NH2:20])[CH:21]=[CH:22][CH:23]=3)=[CH:7][N:6]2[N:8]=1)([CH3:14])([CH3:13])[CH3:12]

Participants

3

Reactant 2

HCID 104682Benzenamine, 3-ethynyl-HCID 583166976-Bromo-2-tert-butylpyrazolo[1,5-a]pyrimidine

Product 1

HCID 53247453HCID 53247453, compound

Procedure

The title compound, light yellow solid, MS: m/e=291.2 (M+H+), can be prepared in accordance with the general method of example 1 from 6-bromo-2-tert-butyl-pyrazolo[1,5-a]pyrimidine (example 9, step 1) and 3-ethynylaniline.

Sources & evidence

ORD record
ord-32fff654171b43c7a339bc6885a3245c
Source dataset
uspto-grants-2015_01
Patent number
US08933094B2

Reaction notes

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