Phenylacetylene → HCID 53247456, compound

HRID 1426227Notes

Reaction equation

Br[C:2]1[CH:3]=[N:4][C:5]2[N:6]([N:8]=[C:9]([CH:11]([CH3:13])[CH3:12])[CH:10]=2)[CH:7]=1.[C:14]1([C:20]#[CH:21])[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1>>[CH:11]([C:9]1[CH:10]=[C:5]2[N:4]=[CH:3][C:2]([C:21]#[C:20][C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=3)=[CH:7][N:6]2[N:8]=1)([CH3:13])[CH3:12]

Participants

Reactant 2

HCID 10821Phenylacetylene

HCID 58316722HCID 58316722, compound

Product 1

HCID 53247456HCID 53247456, compound

Procedure

The title compound, a brown solid, MS: m/e=245.2 (M+H+), can be prepared in accordance with the general method of example 1 from 6-bromo-2-isopropyl-pyrazolo[1,5-a]pyrimidine (example 38, step 1) and phenylacetylene.

Sources & evidence

ORD record: ord-ad5fcee753f74debac232eddc6de0f68
Source dataset: uspto-grants-2015_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08933094B2

Reaction notes

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