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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1426235Generated: November 2, 2026

2-Pyridinamine, 5-iodo- → Acetic acid 2-(5-iodo-pyridin-2-ylcarbamoyl)-2-methyl-propyl ester

https://huagongshe.com/reaction/1426235

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Pyridinamine, 5-iodo-HCID 88579—
Reactant2,2-Dimethyl-3-acetyloxypropionyl chlorideHCID 11194663—
ProductAcetic acid 2-(5-iodo-pyridin-2-ylcarbamoyl)-2-methyl-propyl esterHCID 58316716—

Reaction Steps

The title compound, a white solid, MS: m/e=363.2 (M+H+), can be prepared in accordance with the general method of example 39, step 1 from 2-amino-5-iodopyridine and acetic acid 2-chlorocarbonyl-2-methyl-propyl ester (example 40, step 2).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08933094B2
Source datasetuspto-grants-2015_01
ORD IDord-4c83700b0cff4545a9839f395923f509
Source noteuspto-grants-2015_01