HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Chloro-5-iodo-pyridine → 2-tert-Butyl-6-(5-chloro-pyridin-3-ylethynyl)-[1,2,4]triazolo[1,5-a]pyrimidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Chloro-5-iodo-pyridine | HCID 24229178 | — |
| Reactant | 2-tert-Butyl-6-trimethylsilanylethynyl-[1,2,4]triazolo[1,5-a]pyrimidine | HCID 58316698 | — |
| Product | 2-tert-Butyl-6-(5-chloro-pyridin-3-ylethynyl)-[1,2,4]triazolo[1,5-a]pyrimidine | HCID 53247575 | — |
Reaction Steps
The title compound, a light yellow solid, MS: m/e=312.2/314.1 (M+H+), can be prepared in accordance with the general method of example 43, step 2 from 2-tert-butyl-6-trimethylsilanylethynyl-[1,2,4]triazolo[1,5-a]pyrimidine (example 43, step 1) and 3-chloro-5-iodopyridine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08933094B2 |
| Source dataset | uspto-grants-2015_01 |
| ORD ID | ord-e0300de558c448c081da354f12045db6 |
| Source note | uspto-grants-2015_01 |