Phenylacetylene → HCID 53245754, compound

HRID 1426254Notes

Reaction equation

HRID 1426254 reaction equation
Br[C:2]1[CH:3]=[N:4][C:5]2[N:6]([N:8]=[C:9]([N:11]3[CH2:15][CH2:14][CH2:13][CH2:12]3)[N:10]=2)[CH:7]=1.[C:16]1([C:22]#[CH:23])[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1>>[C:16]1([C:22]#[C:23][C:2]2[CH:3]=[N:4][C:5]3[N:6]([N:8]=[C:9]([N:11]4[CH2:15][CH2:14][CH2:13][CH2:12]4)[N:10]=3)[CH:7]=2)[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1

Participants

3

Reactant 2

HCID 10821PhenylacetyleneHCID 58316725HCID 58316725, compound

Product 1

HCID 53245754HCID 53245754, compound

Procedure

The title compound, a light brown solid, MS: m/e=290.2 (M+H+), can be prepared in accordance with the general method of example 1 from 6-bromo-2-pyrrolidin-1-yl-[1,2,4]triazolo[1,5-a]pyrimidine (example 51, step 1) and phenylacetylene.

Sources & evidence

ORD record
ord-7f5bbbf9e9d9417db92f71b27ee55c15
Source dataset
uspto-grants-2015_01
Patent number
US08933094B2

Reaction notes

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