Triacetoxyperiodinane → HCID 86666506, compound

Participants

Reaction Steps

To a solution of tert-butyl 4-[3-bromo-5-(hydroxymethyl)phenoxy]piperidine-1-carboxylate (0.47 g, 1.2 mmol) in DCM (20 mL) at 0° C. was added Dess-Martin periodinane (0.67 g, 1.6 mmol). After stirring for 2 hours, the reaction solution was poured into saturated NaHCO3, and extracted with DCM (3×). The combined extracts were washed with brine. The organic layer was dried over sodium sulfate, decanted and evaporated to give the desired product that was used without further purification.

Provenance & Evidence