Dimethylamine → HCID 69673572, compound

HRID 1426350Notes

Reaction equation

[CH:1]([C:3]1[CH:4]=[C:5]([CH:20]=[C:21]([C:23]([F:26])([F:25])[F:24])[CH:22]=1)[O:6][CH:7]1[CH2:12][CH2:11][N:10]([C:13]([O:15][C:16]([CH3:19])([CH3:18])[CH3:17])=[O:14])[CH2:9][CH2:8]1)=O.[CH3:27][NH:28][CH3:29]>>[CH3:27][N:28]([CH2:1][C:3]1[CH:4]=[C:5]([CH:20]=[C:21]([C:23]([F:26])([F:25])[F:24])[CH:22]=1)[O:6][CH:7]1[CH2:12][CH2:11][N:10]([C:13]([O:15][C:16]([CH3:19])([CH3:18])[CH3:17])=[O:14])[CH2:9][CH2:8]1)[CH3:29]

Participants

Reactant 2

HCID 674Dimethylamine

HCID 86666508HCID 86666508, compound

Product 1

HCID 69673572HCID 69673572, compound

Procedure

The title compound was prepared according to the method of Example 41, Step 2 using tert-butyl 4-[3-formyl-5-(trifluoromethyl)phenoxy]piperidine-1-carboxylate and dimethylamine as starting materials. LCMS (M+H)+: 403.2.

Sources & evidence

ORD record: ord-ed4b8e5261a940089864c008b2eb6088
Source dataset: uspto-grants-2015_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08933085B2

Reaction notes

Loading…