4-(Trifluoromethoxy)aniline → 3-[4-[4-(Trifluoromethoxy)anilino]piperidin-1-yl]butanenitrile
Reaction equation
[F:13][C:14]([O:15][c:16]1[cH:17][cH:18][c:19]([NH2:20])[cH:21][cH:22]1)([F:23])[F:24].[O:1]=[C:2]1[CH2:3][CH2:4][N:5]([CH:8]([CH2:9][C:10]#[N:11])[CH3:12])[CH2:6][CH2:7]1>>[CH:2]1([NH:20][c:19]2[cH:18][cH:17][c:16]([O:15][C:14]([F:13])([F:23])[F:24])[cH:22][cH:21]2)[CH2:3][CH2:4][N:5]([CH:8]([CH2:9][C:10]#[N:11])[CH3:12])[CH2:6][CH2:7]1Participants
3
Sources & evidence
- ORD record
- ord-d74577200b384a27ac7f0356358f3034
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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