HCID 67397251, compound → HCID 67396369, compound

Participants

Reaction Steps

To a solution of tert-butyl {[1-{[4-(benzyloxy)phenyl]sulfonyl}-4-fluoro-5-(2-fluoropyridin-3-yl)-1H-pyrrol-3-yl]methyl}methylcarbamate (360 mg) in ethyl acetate (30 mL) was added 10% palladium carbon (50% containing water, 350 mg) under a nitrogen atmosphere, and the mixture was stirred for 1 hr under a hydrogen atmosphere. The reaction mixture was filtrated, and the filtrate was concentrated under reduced pressure to give the title compound as a colorless oil (yield 300 mg, quantitative).

Provenance & Evidence