Hydrogen chloride-ethyl acetate → HCID 67396643, compound

Participants

Reaction Steps

tert-Butyl {[5-(2-cyanopyridin-3-yl)-1-(phenylsulfonyl)-1H-pyrrol-3-yl]methyl}methylcarbamate (250 mg) was dissolved in ethyl acetate (5 mL) and methanol (3 mL), and 4 mol/L hydrogen chloride-ethyl acetate solution (3 mL) was added. The mixture was stirred at room temperature for 4 hr, and concentrated under reduced pressure. The obtained residue was recrystallized from ethanol to give the title compound as colorless crystals (yield 127 mg, 59%).

Provenance & Evidence