Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Isopropanol | HCID 3776 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | HCID 86619831 | HCID 86619831 | — |
| Product | HCID 86619830 | HCID 86619830 | — |
Reaction Steps
1-tert-Butoxy-3-fluoro-5-isothiocyanatobenzene (24.0 g) and triethylamine (10.9 g) are dissolved in iso-propanol (150 ml). The reaction mixture is refluxed for 18 hours and the solvent is removed by vacuo. The crude product is dissolved in hexane: diethyl ether (19:1). The diethyl ether is removed in vacuo and the solution is cooled to 0° C. for 3 hours. The solution is filtered to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08933108B2 |
|---|
| Source dataset | uspto-grants-2015_01 |
|---|
| ORD ID | ord-e9c21e0a133d41aab1374f00b10ed18f |
|---|
| Source note | uspto-grants-2015_01 |
|---|
