Nitric Acid → HCID 86730355, compound

HRID 1427054Notes

Reaction equation

HRID 1427054 reaction equation
[N+:1]([O-])([OH:3])=[O:2].[CH2:5]([O:12][C:13]1[CH:18]=[C:17](/[CH:19]=[CH:20]/[N+:21]([O-:23])=[O:22])[CH:16]=[CH:15][C:14]=1[O:24][CH2:25][CH2:26][CH2:27][O:28][CH3:29])[C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1>C(O)(=O)C>[CH2:5]([O:12][C:13]1[CH:18]=[C:17](/[CH:19]=[CH:20]/[N+:21]([O-:23])=[O:22])[C:16]([N+:1]([O-:3])=[O:2])=[CH:15][C:14]=1[O:24][CH2:25][CH2:26][CH2:27][O:28][CH3:29])[C:6]1[CH:7]=[CH:8][CH:9]=[CH:10][CH:11]=1

Participants

4

Reactant 2

HCID 944Nitric AcidHCID 86730354HCID 86730354, compound

Product 1

HCID 86730355HCID 86730355, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

69% Nitric acid (16 mL, 249 mmol) was added to a liquid mixture of (E)-2-(benzyloxy)-1-(3-methoxypropoxy)-4-(2-nitrovinyl)benzene described in Production Example 32-3 (22.6 g, 65.9 mmol) in acetic acid (150 mL) at room temperature. The liquid mixture was stirred at mom temperature for 6 hours. The reaction liquid was transferred into an ice bath, then the precipitate was collected by filteration and washed with water to quantitatively obtain the title compound.

Workup

  1. customThe reaction liquid
  2. customwas transferred into an ice bath
  3. customthe precipitate was collected by filteration
  4. washwashed with water

Sources & evidence

ORD record
ord-0805d5867a354102af82784b51198b70
Source dataset
uspto-grants-2015_01
Patent number
US08933099B2

Reaction notes

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