HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Pentanol → HCID 69086263, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Pentanol | HCID 6276 | — |
| Reactant | 2-Pentanol | HCID 22386 | — |
| Reactant | 7-methyl-9-oxo-thioxanthene-3-carbonyl Chloride | HCID 10850940 | — |
| Reactant | HCID 22292735 | HCID 22292735 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 69086263 | HCID 69086263 | 71.6% |
Reaction Steps
1.0 g (11.36 mmoles) of pentan-1-ol (containing also -pentan-2-ol) and 1.0 g (9.90 mmoles) of triethyl amine chloride are added to the CH2Cl2 solution containing 2.26 g (7.41 mmoles) of 7-methyl-9-oxo-thioxanthene-3-carbonyl chloride. After approximately 1 hour at room temperature under stirring, the mixture is poured in water, the organic phase is separated and washed again with water. The organic phase is then separated, dehydrated and after purification on a flash column (SiO2— eluent: CH2Cl2:AcOEt 8:2) it is dried, obtaining 1.74 g (71.6%) of a yellow solid with the following spectral properties:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08933142B2 |
| Source dataset | uspto-grants-2015_01 |
| ORD ID | ord-1de5f6261a3f47b98d1680ba0f77c100 |
| Source note | uspto-grants-2015_01 |