Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Nitromethane | HCID 6375 | — |
| Reactant | 5-chloro-1H-indole-2,3-dione | HCID 87203 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 24895521 | HCID 24895521 | — |
Reaction Steps
5-chloroisatin (0.09 g) and nitromethane (0.1 ml) were added to water and the reaction mixture was vigorously stirred at a temperature of 30° C. for 24 hours. The obtained product was extracted with ethyl acetate and purified by silica gel column chromatography using ethyl acetate/hexane as eluents to afford pure product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08933248B2 |
|---|
| Source dataset | uspto-grants-2015_01 |
|---|
| ORD ID | ord-336cca597ff44e0c89f23a5a9e717a9c |
|---|
| Source note | uspto-grants-2015_01 |
|---|
